任职要求/岗位职责
The Zhe Jiang Medicine Ltd. is looking for a Protein Analytics Scientist to provide expertise in developing our ADC drug. This individual will execute early stage purification and analytics, to ensure drug like properties, assist in cross functional development of research and development strategy, plan and coordinate the resources for the protein analytics function. The candidate identifies and conducts experiments to evaluate physicochemical properties of new biologic entities (antibody-like proteins) to identify any liabilities that could impact in vivo pre-clinical evaluations and drug product development. Responsibilities: The successful candidate will use his/her targeted skill set to accomplish the following responsibilities: Serve as analytical subject matter expert to support and advise design of characterization studies, data analysis and investigations Design and execution of analytical studies including utilizing protein chemistry and separation sciences to support our current development. Interpret results, assist in authoring technical protocols reports, analytical method descriptions and analytical CMC sections in regulatory documents Develop and execute analytical methods for protein expression systems, process development, protein characterization, and pre-formulation Leverage latest advances in protein analytics to develop, optimize, troubleshoot, remediate, qualify, validate and transfer analytical methods Develop and validate analytical methods in support of formulation, drug product development and stability studies. Qualifications : PhD in chemistry, biochemistry with 5+ years’ industrial experience in supporting method development and testing of commercial or clinical protein products Expertise in liquid chromatography, protein chemistry and mass spectrometry of protein molecules, experience in LC and LC-MS method development and qualification as well as hands on knowledge and experience with immunoassays (i.e., ELISA) Demonstrated success during a minimum 5-year industry experience in a leadership role, with a focus on pre-clinical to Phase I/II/III biologics development She or he should be a dynamic, independent, flexible, well-organized, pro-active, collaborative-minded individual interested in contributing to excellent research science in a fast-paced entrepreneurial environment.有兴趣的请投递简历至:hr@novo-biotech.com
企业介绍
浙江海隆生物科技有限公司是一家拥有雄厚海外背景的生物医药研发企业。公司总投资6,000万元人民币,注册资本1,500万元,落户于绍兴市滨海新城?蛋白质组学与基因组学技术是公司的核心技术,利用该技术平台开展产品自主研发、生物医学外包业务及动物疫病检测服务。 公司于2012年11月注册,2013年8月实验室正式投入运行。经过两年半的筹备和发展,公司现已拥有技术团队达23人,其中海外归国人员5人,硕士以上学历人员占90%以上,博士6人,包括中国科学院院士在内的海内外著名合作顾问/教授十余人。海隆公司依托世界一流的研发设备(投资超3,000万元人民币)与高水准的人才资源,已开发建立了多项技术平台,包括:1、基因工程平台(各种基因工程载体构建、定点突变、Sub-cloning、DNA质粒制备);2、蛋白质工程平台(原核表达系统、真核表达系统、昆虫细胞表达系统);3、分子探针检测平台(PCR/RT-PCR病原菌与病毒检测;ELISA抗体效价检测;细胞因子和细胞免疫流式细胞术检测);4、单克隆抗体生产平台等;5、稳定细胞株筛选;6、多抗体生产制备;7、反向遗传操作。 目前,已研发出猪瘟疫苗、猪圆环病毒疫苗产品,在研的产品有奶牛乳房炎疫苗、猪腹泻疫苗、猪蓝耳疫苗等动物系列疫苗;外包服务可提供人用类医药研发服务外包和动物类医药研发服务外包。 浙江海隆生物科技有限公司自成立以来,的收获是赢得了众多志同道合的朋友。公司遵循“业务精益求精,对客户服务真诚、细致与耐心”公司文化,“客户的信任是我们的荣幸、客户的需求是我们的责任”的经营理念,我们期待与您的合作,携手共创辉煌。海隆的明天更美好!